Autologous Protein Serum

What Is Autologous Protein Serum?

Autologous Protein Serum (APS) is an innovative treatment designed to relieve pain and improve joint function in patients with osteoarthritis (OA) of the knee. Dr Bassam Moses performs this procedure by using the patient’s own blood to create a serum enriched with anti-inflammatory proteins. This serum is then injected into the affected joint, targeting inflammation—a key factor in osteoarthritis progression. APS is a type of autologous protein solution therapy that leverages the body’s natural healing ability to manage symptoms and enhance joint health.

Who Is Suitable for Autologous Protein Serum?

APS is ideal for patients with mild to moderate knee osteoarthritis who have not found adequate relief from conservative treatments. It is also an option for individuals looking to delay or avoid knee surgery due to its minimally invasive nature. However, APS may not be suitable for:

Patients with Severe Osteoarthritis: Those with advanced joint damage or deformities may require surgical intervention.
Individuals with Active Joint Infections: APS is not recommended if there is an active infection in or near the knee.
Patients with Blood Disorders: Individuals with clotting disorders or certain medical conditions should consult their doctor before considering APS.

A thorough evaluation by Dr Moses is essential to determine if APS is the right treatment option.

Benefits of Autologous Protein Serum

Pain Reduction: APS can significantly alleviate knee pain caused by osteoarthritis.
Improved Joint Function: Many patients experience enhanced mobility and flexibility after treatment.
Anti-Inflammatory Effects: The therapy directly targets and reduces inflammation.
Minimal Downtime: The procedure is minimally invasive, allowing for a quick return to daily activities.
Natural Approach: Since APS uses the patient’s blood, the risk of adverse reactions is minimised.

Alternative Options to Autologous Protein Serum

Patients who are not candidates for APS or prefer other treatments may consider:

Conservative Treatments: Physical therapy, NSAIDs, acetaminophen, and corticosteroid injections.
Orthobiologic Treatments: Platelet-rich plasma (PRP) therapy, stem cell therapy, and hyaluronic acid injections.
Surgical Options: Arthroscopy, osteotomy, or total knee replacement for severe cases.
Lifestyle Modifications: Weight management, low-impact exercise, and dietary changes to support joint health.

Preparation for Autologous Protein Serum Therapy

Before undergoing APS therapy, patients should:

Consult a Specialist: Discuss symptoms, medical history, and treatment goals with an orthopedic expert.
Undergo Diagnostic Tests: X-rays or MRIs may be required to assess the severity of osteoarthritis.
Review Medications: Some medications may need to be paused before the procedure.
Address Infections: Any existing infections or skin conditions near the knee should be treated beforehand.
Follow Pre-Procedure Instructions: This may include fasting or hydration guidelines.
Arrange Transportation: Since mild discomfort or mobility limitations may occur post-procedure, arranging a ride home is recommended.

What Happens During Autologous Protein Serum Therapy?

Blood Draw: A small sample of blood is taken from the patient.
Serum Preparation: The blood is processed to concentrate anti-inflammatory proteins.
Injection: The prepared serum is injected into the knee joint under imaging guidance for precise placement.

Post-Procedure Expectations

After the procedure, patients may experience mild swelling or discomfort, which can be managed with rest and ice. Pain relief and improved joint function usually develop gradually over several days to weeks.

Recovery Plan

Rest and Ice: Apply ice packs and limit strenuous activity for the first few days.
Gradual Activity Resumption: Patients should increase movement gradually based on medical advice.
Physical Therapy: Strengthening and flexibility exercises can optimise recovery.
Regular Monitoring: Follow-up appointments will track progress and determine if additional treatments are needed.

Prognosis of Autologous Protein Serum

Most patients experience significant pain relief and improved joint function, with benefits lasting up to two years. APS may also help delay the need for more invasive procedures like knee replacement surgery.

Risks of Autologous Protein Serum

APS is generally safe, but potential risks include:

Injection Site Reactions: Mild swelling, bruising, or temporary discomfort.
Infection: Rare but possible if proper sterilisation is not maintained.
Allergic Reactions: Though unlikely, sensitivity to components in the serum may occur.
Limited Effectiveness: Some patients may not experience the desired level of pain relief.

Consequences of Delaying Treatment

Postponing APS therapy can lead to worsening osteoarthritis symptoms, increased dependency on pain medications, and a faster progression toward invasive surgical interventions. Early treatment can help preserve joint function and improve long-term mobility.